RT700 Flow-through Cell Dissolution System
The RT700 Flow-through Cell Dissolution System operates as a precise evaluation instrument that examines sustained-release products along with suspensions and liposomal drugs. The system allows testing with open-loop and closed-loop sampling operations to suit diverse dissolution requirements. It operates with seven flow cells which support accurate analysis through dual flow rate testing functions. This system includes water bath heaters which are integrated with real-time temperature control systems for accurate environmental monitoring. The patented filtration method operates by reducing back pressure so samples can process optimally.
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- Patented Filter Components
- Immersion Thermostatic Water Baths
- 0/120Hz Dual-pulse Mode
- Compatible with Both Open and Closed-loop Modes
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Description
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This device includes a precise syringe pump that has a separate overpressure safeguard alongside leak detection functionality. The Teflon tubing on the system functions to stop sample adsorption and eliminate residue formation.
Different testing scenarios can be handled through the use of adaptable sample racks and filter membranes of multiple dimensions. The precise temperature control relies on real-time monitoring sensors to operate with reliability.
Features
Dual Flow Rates
7-channel flow cell device supports testing at 2 flow rates simultaneously.
Integrated Heating
The integrated water bath heating and stirring device can meet the experimental requirements of seven sample solvent bottles and one rehydration solvent bottle.
Real-Time Monitoring
7 independent temperature sensors monitor the temperature in each channel in real time.
Pharmacopoeia Compliance
We can provide various flow cells included in the regulations to meet the dissolution test requirements of various samples.
Teflon pipe
Adopt Teflon tubing with high chemical stability and high adsorption resistance to effectively avoid adsorption and residue.
Multi-size sample racks
Sample racks for 70mL sample bottles, 10mL test tubes and liquid phase vials.
High precision syringe pump
Adopt high-precision constant flow pump, can set non-pulsation mode and pulsation mode (120Hz). Each channel is equipped with independent overpressure protection and leakage detection device.
Efficient filtration
Patented multiple filtration device effectively reduces filtration back pressure.
Multi-mode sampling system
One machine can realize closed-loop and open-loop sampling.
Filtration membrane diversity
Filter membranes of different materials and pore sizes are available
Application
The flow cell method can provide better in vitro and in vivo correlation and better discrimination than traditional dissolution methods. It is more suitable for the study of in vitro drug release in the research and development stage and can better predict its bioavailability.
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Soft Capsules
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Sustained-release tablets
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Liposomes
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Suspension
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Nanochip
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Eye drops
Specifications
Product Brochure
Flow-Through Cell Dissolution Apparatus
| Length ×Width× Height: ~ 80 cm × 62 cm ×60 cm |
Temperature resolution: 0.1 ℃ |
| Number of channels: 7 |
Temperature control error:<±0.2℃ |
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Temperature control range: room temperature +5°C-50°C |
Temperature difference between the cells: <±0.5℃ |
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Both open-loop mode and closed-loop mode are available |
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Medium Conveying Workstation
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Length × Width × Height:~98cm× 63cm×55cm |
Velocityresolution: 0.1mL/min |
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The stirring working position:8 |
Velocity error: <±5% |
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Stirring speed error: ≤± 10% |
Temperature control range: room temperature +5°C-50°C |
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Velocity range: 1~40mL/min |
Temperature probe error: ≤± 0.5 ℃ |
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Temperature resolution: 0.1 ℃ |
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Automatic Sampling Workstation
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Length × Width × Height:~75cm×63 cm×56 cm |
Maximum sampling times: 45(closed-loop mode), unlimited(open-loop mode) |
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Number of channels: 7 |
Sampling volume error: ≤± 2% (closed-loop mode), ≤± 5% (open-loop mode) |
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Test tube type:70 ml sample bottle,10 ml test tube, Liquid Phase Vial |
Pump type: syringe pump |
Operating System
| Meet the requirements of FDA21 CFR Part 11 |
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