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RT600-ST Automated Dissolution Sampling Apparatus

The RT806 is structured as a small-sized Vertical Franz Diffusion Cell system that includes heating functionalities with a built-in stirrer module. The device comes with a portable layout that makes it easy to place in any location for convenient operation. The system delivers detailed temperature and speed management needed for reliable transdermal testing. The system meets the performance requirements outlined in USP<1724> for the simulation of in vitro release and permeation procedures. Bubbles are prevented through the filling point design which results in dependable experimental outcomes.

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High Anti-adsorption Pipeline
High-precision Sampling

Complete Filtration Solutions
Optional Online Dilution

The device follows USP<1724> specifications to perform in vitro release tests and permeation studies that evaluate creams gels and patches. The instrument design includes a filling point that prevents bubbles from forming which leads to precise and dependable outcomes.
The RT600-ST performs automatic preheating functions and incorporates covered dissolving cups that maintain uniform testing conditions. Switching methods with this instrument becomes possible because of its paddle-basket co-axial design that requires no recalibration.

The automatic sample collection system has enhanced efficiency by designing a capacity to handle 120 vials in liquid phase format. Continuous filtration occurs through dual online filters that stop equipment clogs from forming.

Features

Automatic preheating

With the automatic preheating function of medium, the instrument can be set to automatically start constant temperature water bath heating at the specified time.

Covered Dissolving Cups

Dissolving cups are automatically centered for fast and accurate installation and greater durability.

Paddle basket co-axial design

Suitable for all kinds of regulations included in the test method. Not necessary to readjust the height of dissolution unit after switching dissolution method.

Automatic Synchronous Dosing

Eliminate the time difference of dosing and the time of dosing can be tracked.

Precise sampling

High-precision sampling pump which can effectively provide accurate and precise sampling.

Pipeline System

Teflon pipeline system with high chemical stability and high anti-adsorption was used to avoid corrosion of sampling pipeline or sample adsorption.

Automatic Online Filtering

Dual on-line filters can be installed, and the instrument can automatically realize the function of embellish washing saturated filter.

Automatic Sample Collection

Comes with a 120-position sample tray for 1.5mL liquid phase vials and a 10mL test tube rack.

Innovative Design

Support for changing solvent volume and stirring speed during the dissolution process

Data Cloud System

Raytor cloud system can connect at least 250 different types of experimental instruments at the same time to realize intelligent management.

Application

Basket and paddle methods are the most commonly used legal dissolution methods in national pharmacopoeias and were the first dissolution methods introduced into pharmacopoeias. They are mainly used for quality control (QC) of pharmaceutical products.

Oral Tablets
Patch
semi-solid preparations
Injection
Intrinsic Dissolution Rate of API

Specifications

Product Brochure

General Dissolution System

Length ×Width× Height(Fully Raised): 63 cm × 56cm ×96 cm	Dissolution Vessel Number: 8
Setting Range: 20-250 rpm (RPM)	RPM Resolution: 0.01RPM
Steady Speed Error: ≤±0.3RPM	Temp. Accuracy: ≤±0.2℃
Temp. Resolution: 0.01 ℃	Level: ＜ 0.5°
Vessel Verticality: 90°±0.5°	Shaft Verticality: 90°±0.5°
Centering Deviation: ＜ ±2.0 mm	Depth Positioning Deviation: ＜ ±1.0 mm
Shaft Wobble: ＜ ±1.0 mm	Basket Wobble: ＜ ±1.0 mm

Automatic Sampling Workstation

Length ×Width× Height: 40 cm ×70cm ×70 cm

Maximum Settable Sample Number: 20

Sampling Range: 1 ~ 20ml

Minimum Sampling Interval:

First Sampling Point: 3 minutes
Follow up Routine Sampling Point: 5 minutes

Maximum Working Time: 720 hours

Sampling Precision: ≤±1%

Operating System

Meeting FDA21 CFR Part 11

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