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RT600 Dissolution Apparatus

The device operates as a small and reliable platform to perform in vitro release tests and permeation experiments. This device meets all parameters of USP <1724> which allows precise simulation of drug diffusion processes in creams gels and patches. The system includes automatic preheating along with covered dissolving cups and it provides synchronous dosing for precise reproducible outcomes. The system’s design logic manages to reduce turbulent conditions and stops bubbles from forming which leads to dependable experimental outcomes. The system can store an unlimited amount of data and implements validation requirements according to FDA 21 CFR Part 11 to deliver strict pharmaceutical quality evaluation.

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Covered Dissolving Cups
Convenient Sampling

Automatic Synchronous Dosing
Infinite Data Storage

The system achieves better accuracy through its easy sampling process and automated needle positioning feature. The system features a small operational design that enables laboratory staff to place it easily in diverse testing areas.

The paddle-basket co-axial design of RT600 allows easy method switching within dissolution experiments without needing any mechanical adjustment. This round-cornered water bath heats uniformly while remaining easy to clean

Features

Automatic preheating

With the automatic preheating function of medium, the instrument can be set to automatically start constant temperature water bath heating at the specified time.

Convenient sampling

Non-resident sampling needles to reduce turbulence generation. The sampling needle can be automatically positioned according to the set solvent volume.

Covered Dissolving Cups

Dissolving cups are automatically centered for fast and accurate installation and greater durability.

Paddle basket co-axial design

Suitable for all kinds of regulations included in the test method. Not necessary to readjust the height of dissolution unit after switching dissolution method.

Round corner water bath

The one-piece, rounded corner design of the water bath ensures that there are no dead corners in the water circulation for heating and cleaning.

Automatic Synchronous Dosing

Eliminate the time difference of dosing, and the time point of dosing can be tracked.

Application

Basket and paddle methods are the most commonly used legal dissolution methods in national pharmacopoeias and were the first dissolution methods introduced into pharmacopoeias. They are mainly used for quality control (QC) of pharmaceutical products.

Oral Tablets
Patch
Semi-solid preparations
Injection
Intrinsic Dissolution Rate of API

Specifications

Product Brochure

General Dissolution System

Length ×Width× Height(Fully Raised)：~ 63 cm × 56cm ×96 cm	Dissolution Vessel Number: 8
Setting Range: 20-250 rpm (RPM)	RPM Resolution: 0.01RPM
Steady Speed Error: ≤±0.3RPM	Temp. Accuracy: ≤±0.2℃
Temp. Resolution: 0.01 ℃	Level: ＜ 0.5°
Vessel Verticality: 90°±0.5°	Shaft Verticality: 90°±0.5°
Centering Deviation: ＜ ±2.0 mm	Depth Positioning Deviation: ＜ ±1.0 mm
Shaft Wobble: ＜ ±1.0 mm	Basket Wobble: ＜ ±1.0 mm

Operating System

Meeting FDA21 CFR Part 11

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