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RT3 Reciprocating Cylinder Apparatus

The RT3 Reciprocating Cylinder operates as an advanced dissolution testing equipment that duplicates in vivo mechanical stress conditions by offering exact control of bicurious motions. The device integrates an automatic vessel cover which reduces evaporation losses while offering single-piece water baths that promote efficient heating. Users can modify the reciprocating stroke together with the rate and immersion time through flexible settings accessible by the system. A precise filtration device with high accuracy filters drug matter to generate proper test results. The device operates through an 8.4-inch touchscreen interface that makes operation easy by meeting all requirements from FDA 21 CFR Part 11.

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Efficient Anti-volatilization
Low Operational Noise

Flexible Reciprocating Parameterization
Intimate Operation Design

Description
Using improved hydrodynamic forces allows the RT3 to excel in functional gummies and enteric tablet assessment as well as testing for soft capsules and orally disintegrating tablet systems. Lab testing of drug release becomes more realistic because the device emulates pH conditions found in digestive tracts.

The RT3 equipment delivers deterministic and exact dissolution outcomes because of its robust construction together with its exact engineering. The system delivers simplified workflow management which enzymes data integrity to fulfill regulatory requirements..

Features

Co-axial Mounting Bracket

The coaxial split design makes it quickly to replace the reciprocating cylinder with other reciprocating holder.

Automatic Dissolution Vessel Cover

The cover of dissolution vessel can automatically open and close, effectively reducing the evaporation loss of the dissolution medium.

One-piece water bath

One-piece rounded corners water bath with no dead spots and can be thoroughly drained

Filtration device

Various sizes of cylindrical filter elements can be fitted to filter out large particles of drugs that are not fully dissolved.

Flexible setting of experimental parameters

The reciprocating rate, reciprocating stroke, immersion time and drain time can be set.

Wide range of dissolution vessel sizes

Available with 300mL or optional 1000mL dissolving cup for testing.

User-computer Interface

8.4-inch touch screen, preinstalled with the Raytor dissolution operating system, meeting the data integrity requirements.

Application

Compared to paddle and basket methods, the reciprocating cylinder method is able to provide more enhanced hydrodynamic forces by adjusting the reciprocating stroke and reciprocating frequency. It better simulates the mechanical stresses of chewing or in the body. It also supports changing the pH of the dissolution medium to simulate human gastrointestinal conditions.

Functional Gummies
Enteric tablets
Soft capsule
orally disintegrating tablets

Specifications

Product Brochure

Reciprocating Cylinder Dissolution System

Length ×Width× Height(Fully Raised): 80cm × 63cm ×100 cm	Dissolution Vessel Row Number: 7 tubes ×6 Rows（300mL Stand Vessel）
Dissolution System Level: ≤ 0.3°	Shaft Verticality: ≤ 90°± 0.5°
Temperature Control Range: Ambient Temperature ~ 50℃	Temp. Resolution: 0.1 ℃
Temp. Accuracy: ≤ ± 0.2℃	Vessels’ Temp. Difference: ≤ ± 0.5℃
Adjustable Range of Reciprocating Stroke: 2 ~ 10 cm	Error of Reciprocating Stroke: ≤ ± 0.1 cm
Adjustable Range of Reciprocating Rate: 4 ~ 60 DPM	Error of Reciprocating Rate: ≤ ±5%
Maximum Running Time: 600 (Hours)

Operating System

Meet the requirements of FDA21 CFR Part 11

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