NCE P3 High-throughput Compound Screening Apparatus
NCE P3 High-throughput Compound Screening presents itself as an automated scientific instrument that performs compound screening work while conducting related physical and chemical constant measurements. The device performs accurate measurements of drug physical and chemical constants for pre-drug prescriptions through titration by determining drug dissociation constants and oil-water partition coefficients to support innovative drug development screening.
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- Automatic liquid filling robot arm
- Real-time monitoring of absorbance
- Graphical representation of experimental results
- Reduce the amount of sample required for the experiment
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Description
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PKa Test
Compound PKa measurement operates through titration method principles. Full-spectrum monitoring together with automated data collection and analysis functions operate continuously throughout the experimental duration.
log Test
The spectroscopy device automatically measures the log D value which can then be transformed into log P through using the PKa value.
log S Test
An automatic turbidity method in the system measures compound kinetic solubility while the built-in software calculates the value of the log.
Features
Robotic arm structure
The device is equipped with an robotic arm, the probe is integrated in it, so that the entire test process is automated.
Multi-reactor hole design
Equipped with 14 reaction kettle holes, a set of tests can automatically measure multiple compounds to meet high-throughput test requirements.
Cleaning tank
The probe on the robot arm will be automatically cleaned before each contact with the sample to avoid cross contamination, which will affect the test results.
Built-in software algorithm
Based on the test results, the algorithm can automatically calculate the corresponding physical and chemical constant values. No additional data calculation is required.
Application
For the characteristic analysis of compounds, accurate determination of drug physicochemical constants in pre-drug prescription research, including automated determination of drug dissociation constants and oil-water partition coefficients, providing important reference for innovative drug development and compound screening
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pKa Test
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logD Test
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logS Test
Specifications
Product Brochure
Physicochemical Parameter Analyzer
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Temperature control range: room temperature ~ 50℃ |
Temperature difference: ≤±0.5℃ |
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Optical path range: 200~850nm |
Light source type: deuterium lamp |
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Light source life: >1000h |
Wavelength resolution; 1nm |
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PH measurement range: 1~12 |
Stirring range: 100~1000rpm |
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Speed error: ≤±5% |
Electrode type: Ag/AgCl electrode |
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Minimum collection interval: 1s |
Medium pump volume range: 0~50mL |
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Titration pump volume range: 0~2.5mL |
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