NCE DP Dissolution and Permeation Testing Apparatus
Real-time concentration monitoring is possible through the advanced technology platform called NCE DP Dissolution and Permeation Testing. The system performs dissolution and permeation analysis through its biological model coupled with its optical fiber system which duplicates human body procedures to achieve precise measurements. The system provides precise absorbance monitoring to enhance biopharmaceutical classification. Data accuracy relies on Accurate Inside technology and graphical results strengthen analysis effectiveness. The system lowers the consumption of test samples which helps maximize experimental resource utilization.
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- Exclusive patented Accurate Inside algorithm
- Real-time monitoring of absorbance
- Graphical representation of experimental results
- Reduce the amount of sample required for the experiment
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Description
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These devices monitor concentration alterations using their six optical fibers in a perpetual check. The medium switching module functions as an automated system that enhances experiment flexibility by performing medium replacement tasks.
The bionic membrane uses intestinal absorption technology together with the auxiliary software for accurate and reliable data comparison.
Features
Real-time monitoring
The device is equipped with 6 optical fibers, which can monitor the concentration changes of samples in real time during the experiment.
Medium switching module
For experiments that require medium switching, the medium switching module can automatically inject the medium at a specific time to complete the medium switching operation.
Bionic membrane
Bionic membrane is used to construct a permeation model to simulate the absorption of drugs by small intestinal epithelial cells.
Auxiliary analysis software
Auxiliary analysis software can analyze data results and compare different experimental results, making the experimental results clear and easy to understand.
Application
Drugs have complex dissolution and permeation behaviors in the body, so the impact of the in vivo environment on the drug needs to be considered during the early drug development or prescription modification process. For this purpose, it is necessary to construct an in vitro environment that can simulate the in vivo environment for experimental research.
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Intrinsic Dissolution Rate Test
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PH Shift Model
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Permeation Model
Specifications
Product Brochure
Dissolution&Permeation Analyzer
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Wavelength range: 200~750nm |
Absorbance linear range: 0.01~3AU |
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Wavelength accuracy: 1nm |
Detector type: Deuterium lamp |
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Absorbance accuracy: ±0.001AU |
Minimum acquisition frequency: 1 second/time |
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Reactor channel: 6 |
Fiber channel: 6 |
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Light source life: >1000h |
Room temperature range: room temperature~40℃ |
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Temperature error: ±0.5℃ |
Speed range: 100~1000rpm |
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Speed resolution: 1rpm |
Liquid addition accuracy: <1% |
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